Entourage effect, what is it?
CBD, CBG & Terpenes in the full spectrum extract of TerpPens CBD. What belongs together comes together here.
The assumption that the biochemical compounds found in hemp in their entirety work better than individual isolated components alone was first published in 1998 in a study by the Hebrew University of Jerusalem. Other studies and scientific work in recent years have confirmed the existence of the entourage effect.
The results of this research suggest that full-spectrum plant extracts and cannabis flowers are more efficient than the individual, isolated molecules in their pure form. For us, the use of precisely defined full-spectrum hemp extracts - of course in compliance with the legally prescribed THC saturation of a maximum of 0.2% - which are enriched with carefully arranged terpene profiles, represents the future of an effective, easily comprehensible and reproducible use of cannabis.
How the entourage effect works:
- Extracts that reproduce the full spectrum of all the ingredients in a plant can be helpful in many ways.
- Only the interaction of the entire spectrum of contents of a plant enables better bioavailability.
- A full spectrum extract can have an advantage over isolates in overcoming bacterial defense mechanisms.
- In our opinion, only the full spectrum of the substances contained in a plant contributes to the minimization of unwanted side effects of individual active substances contained.
Cannabis has been used medicinally since time immemorial. Initially, interest in the exact molecular composition of the plant lagged somewhat. What was important, however, was the effect and this had already convinced our ancestors for thousands of years.
It only changed fundamentally from the middle of the 20th century. Tetrahydrocannabinol (THC) and cannabidiol (CBD) were first discovered in hemp plants and could be isolated as pure substances. The researchers then became more interested in the plant's mechanisms of action. Cannabis research slowly picked up speed and over time many other ingredients, the entourage effect and finally the endocannabinoid system (ECS) were discovered in 1992.
So far, over 400 molecules and compounds have been discovered and researched in the hemp plant. Of course, this includes primarily cannabinoids, but also a variety of terpenes, flavonoids and other secondary plant substances. However, even at this point in time, research is still not so advanced that one could say that cannabis has now been completely researched.
Again and again new molecules are discovered or the effects of already known cannabionoids are researched in more depth. Various research results indicate that the individual components of hemp have different effects on the body. The special thing about it: They interact synergistically and thus generate and reinforce each other's overall benefits.
This interplay of a full spectrum of ingredients is called the entourage effect.
Best to think of the entourage effect and the molecules involved in it like the cast in a film production.
In our case, CBD and CBG are the main actors. The other cannabinoids and terpenes play secondary roles. Without the team in the background such as the editing, costume designer, light and sound or the mask would not work as a whole. These secondary tasks take on in a full extract, among others the flavonoids and other plant substances. Only if everyone works together can the film be a success in the end.